Bacterial global regulators DksA/ppGpp increase fidelity of transcription

Collisions between paused transcription elongation complexes and replication forks inevitably happen, which may lead to collapse of replication fork and could be detrimental to cells. Bacterial transcription factor DksA and its cofactor alarmone ppGpp were proposed to contribute to prevention of suc...

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Bibliographic Details
Main Authors: Roghanian, Mohammad, Zenkin, Nikolay, Yuzenkova, Yulia
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330370/