De Novo Enzyme Design Using Rosetta3

The Rosetta de novo enzyme design protocol has been used to design enzyme catalysts for a variety of chemical reactions, and in principle can be applied to any arbitrary chemical reaction of interest, The process has four stages: 1) choice of a catalytic mechanism and corresponding minimal model act...

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Bibliographic Details
Main Authors: Richter, Florian, Leaver-Fay, Andrew, Khare, Sagar D., Bjelic, Sinisa, Baker, David
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095599/