Multivariate models to detect genomic signatures for a class of drugs: application to thiopurines pharmacogenomics

Often, analysis for pharmacogenomic studies involving multiple drugs from the same class is completed by analyzing each drug individually for association with genomic variation. However, by completing the analysis of each drug individually, we may be losing valuable information. When studying multip...

Full description

Bibliographic Details
Main Authors: Fridley, B L, Jenkins, G D, Batzler, A, Wang, L, Ji, Y, Li, F, Weinshilboum, R M
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084322/