A critical analysis of the combined usage of protein localization prediction methods: Increasing the number of independent data sets can reduce the accuracy of predicted mitochondrial localization
In the absence of a comprehensive experimentally derived mitochondrial proteome, several bioinformatic approaches have been developed to aid the identification of novel mitochondrial disease genes within mapped nuclear genetic loci. Often, many classifiers are combined to increase the sensitivity an...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Science
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081538/ |