Can abscopal effects of local radiotherapy be predicted by modeling T cell trafficking?

The abscopal effect of radiation describes tumor regression in metastases outside of the field upon treatment of one site, and is mediated by radiation-induced anti-tumor T cells. The ability of radiation to generate an in situ tumor vaccine and improve responses to immunotherapy is under intense in...

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Bibliographic Details
Main Authors: Demaria, Sandra, Formenti, Silvia C.
Format: Online
Language:English
Published: BioMed Central 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869282/