A Soluble Form of the High Affinity IgE Receptor, Fc-Epsilon-RI,
Circulates in Human Serum

A Soluble Form of the High Affinity IgE Receptor, Fc-Epsilon-RI, Circulates in Human Serum

Soluble IgE receptors are potential in vivo modulators of IgE-mediated immune responses and are thus important for our basic understanding of allergic responses. We here characterize a novel soluble version of the IgE-binding alpha-chain of Fc-epsilon-RI (sFcεRI), the high affinity receptor for IgE....

Full description

Bibliographic Details
Main Authors:	Dehlink, Eleonora, Platzer, Barbara, Baker, Alexandra H., LaRosa, Jessica, Pardo, Michael, Dwyer, Peter, Yen, Elizabeth H., Szépfalusi, Zsolt, Nurko, Samuel, Fiebiger, Edda
Format:	Online
Language:	English
Published:	Public Library of Science 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081330/

Similar Items

Fc-Epsilon-RI, the High Affinity IgE-Receptor, Is Robustly Expressed in the Upper Gastrointestinal Tract and Modulated by Mucosal Inflammation
by: Bannert, Christina, et al.
Published: (2012)

Epidermal Langerhans cells from normal human skin bind monomeric IgE via Fc epsilon RI
Published: (1992)

Expression of functional high affinity immunoglobulin E receptors (Fc epsilon RI) on monocytes of atopic individuals
Published: (1994)

Mast cells lacking the high affinity immunoglobulin E receptor are deficient in Fc epsilon RI gamma messenger RNA
Published: (1995)

Human epidermal Langerhans cells express the high affinity receptor for immunoglobulin E (Fc epsilon RI)
Published: (1992)

Human Eosinophils Express the High Affinity IgE Receptor, FcεRI, in Bullous Pemphigoid
by: Messingham, Kelly N., et al.
Published: (2014)

Cotranslational endoplasmic reticulum assembly of FcɛRI controls the formation of functional IgE-binding receptors
by: Fiebiger, Edda, et al.
Published: (2005)

The beta subunit of the Fc epsilon RI is associated with the Fc gamma RIII on mast cells
Published: (1992)

Expression of the Fc-receptor for IgE (Fc epsilon RII, CD23) on alveolar macrophages in extrinsic allergic alveolitis
Published: (1990)

Functional study of a monoclonal antibody to IgE Fc receptor (Fc epsilon R2) of eosinophils, platelets, and macrophages
Published: (1986)

Roles for the High Affinity IgE Receptor, FcεRI, of Human Basophils in the Pathogenesis and Therapy of Allergic Asthma: Disease Promotion, Protection or Both?
by: Youssef, Lama A., et al.
Published: (2010)

Ethanol Inhibits High-Affinity Immunoglobulin E Receptor (FcεRI) Signaling in Mast Cells by Suppressing the Function of FcεRI-Cholesterol Signalosome
by: Draberova, Lubica, et al.
Published: (2015)

Mechanism of formation of human IgE-binding factors (soluble CD23): III. Evidence for a receptor (Fc epsilon RII)-associated proteolytic activity
Published: (1990)

Inhibition of IgE Activity to Bind its High Affinity Receptor (FcεRIα) by Mouse Anti-IgE Cε3∼4 Monoclonal Antibody (QME5)
by: Qiao, Chun Xia, et al.
Published: (2009)

Mapping of the CD23 Binding Site on Immunoglobulin E (IgE) and Allosteric Control of the IgE-FcϵRI Interaction*
by: Borthakur, Susmita, et al.
Published: (2012)

Environmentally relevant metal and transition metal ions enhance Fc epsilon RI-mediated mast cell activation.
by: Walczak-Drzewiecka, Aurelia, et al.
Published: (2003)

Different roles for the Fc epsilon RI gamma chain as a function of the receptor context
Published: (1995)

IgE-antigen complexes enhance Fc epsilon R and Ia expression by murine B lymphocytes
Published: (1988)

Lateral electromigration and diffusion of Fc epsilon receptors on rat basophilic leukemia cells: effects of IgE binding
Published: (1984)

FCεRI Gene Promoter Polymorphisms and Total IgE Levels in Susceptibility to Atopic Dermatitis in Korea
by: Park, Kui Young, et al.
Published: (2011)

Single-Cell Measurements of IgE-Mediated FcεRI Signaling Using an Integrated Microfluidic Platform
by: Liu, Yanli, et al.
Published: (2013)

Carboplatin-induced severe hypersensitivity reaction: Role of IgE-dependent basophil activation and FcεRI
by: Iwamoto, Takuya, et al.
Published: (2014)

Blocking of Histamine Release and IgE Binding to FcεRI on Human Basophils by Antibodies Produced in Camels
by: Khaled, Al-Qaoud, et al.
Published: (2015)

Fluorogen-Activating Proteins Provide Tunable Labeling Densities for Tracking FcεRI Independent of IgE
by: Schwartz, Samantha L., et al.
Published: (2014)

Delayed maturation of CD4- CD8- Fc gamma RII/III+ T and natural killer cell precursors in Fc epsilon RI gamma transgenic mice
Published: (1996)

Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI
by: Kiyoshi, Masato, et al.
Published: (2015)

The high-affinity human IgG receptor Fc gamma receptor I (FcγRI) is not associated with vascular leakage of dengue
by: Mohamad Zamberi, Zaiharina, et al.
Published: (2015)

An Interaction Library for the FcεRI Signaling Network
by: Chylek, Lily A., et al.
Published: (2014)

A single glycan on IgE is indispensable for initiation of anaphylaxis
by: Shade, Kai-Ting C., et al.
Published: (2015)

Lysis with Saponin improves detection of the response through CD203c and CD63 in the basophil activation test after crosslinking of the high affinity IgE receptor FcεRI
by: Hoffmann, Hans Jürgen, et al.
Published: (2005)

Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn
Published: (1994)

Antibody to FcεRIα Suppresses Immunoglobulin E Binding to High-Affinity Receptor I in Allergic Inflammation
by: Hong, Jung Yeon, et al.
Published: (2016)

IgE Enhances Mouse Mast Cell FcεRI Expression In Vitro and In Vivo: Evidence for a Novel Amplification Mechanism in IgE-dependent Reactions
by: Yamaguchi, Masao, et al.
Published: (1997)

IgE-tailpiece associates with α-1-antitrypsin (A1AT) to protect IgE from proteolysis without compromising its ability to interact with FcεRI
by: Quinn, Phyllis M., et al.
Published: (2016)

Soluble CD23 (Fc epsilon RII) and interleukin 1 synergistically induce early human thymocyte maturation
Published: (1990)

Antigen Cross-Presentation of Immune Complexes
by: Platzer, Barbara, et al.
Published: (2014)

Evidence that FcRn mediates the transplacental passage of maternal IgE in the form of IgG anti‐IgE/IgE immune complexes
by: Bundhoo, A., et al.
Published: (2015)

The Importance of Human FcγRI in Mediating Protection to Malaria
by: McIntosh, Richard S, et al.
Published: (2007)

Observing Fcεri Signaling from the Inside of the Mast Cell Membrane
by: Wilson, Bridget S., et al.
Published: (2000)

Negative Regulation of FcεRI-mediated Degranulation by CD81
by: Fleming, Tony J., et al.
Published: (1997)