Carboplatin-induced severe hypersensitivity reaction: Role of IgE-dependent basophil activation and FcεRI

Basophil activation was observed in patients with a history of carboplatin-induced severe hypersensitivity reaction (HR). However, the precise mechanism by which carboplatin induces basophil activation and the associated surrogate markers remains to be elucidated. To investigate whether IgE-dependen...

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Bibliographic Details
Main Authors: Iwamoto, Takuya, Hirai, Hiroyuki, Yamaguchi, Nozomi, Kobayashi, Natsuki, Sugimoto, Hiroko, Tabata, Tsutomu, Okuda, Masahiro
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462369/