Identification and Functional Validation of the Novel Antimalarial Resistance Locus PF10_0355 in Plasmodium falciparum

Identification and Functional Validation of the Novel Antimalarial Resistance Locus PF10_0355 in Plasmodium falciparum

The Plasmodium falciparum parasite's ability to adapt to environmental pressures, such as the human immune system and antimalarial drugs, makes malaria an enduring burden to public health. Understanding the genetic basis of these adaptations is critical to intervening successfully against malar...

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Main Authors: Van Tyne, Daria, Park, Daniel J., Schaffner, Stephen F., Neafsey, Daniel E., Angelino, Elaine, Cortese, Joseph F., Barnes, Kayla G., Rosen, David M., Lukens, Amanda K., Daniels, Rachel F., Milner, Danny A., Johnson, Charles A., Shlyakhter, Ilya, Grossman, Sharon R., Becker, Justin S., Yamins, Daniel, Karlsson, Elinor K., Ndiaye, Daouda, Sarr, Ousmane, Mboup, Souleymane, Happi, Christian, Furlotte, Nicholas A., Eskin, Eleazar, Kang, Hyun Min, Hartl, Daniel L., Birren, Bruce W., Wiegand, Roger C., Lander, Eric S., Wirth, Dyann F., Volkman, Sarah K., Sabeti, Pardis C.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080868/

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