SNP Genotyping Identifies New Signatures of Selection in a Deep Sample of West African Plasmodium falciparum Malaria Parasites

We used a high-density single-nucleotide polymorphism array to genotype 75 Plasmodium falciparum isolates recently collected from Senegal and The Gambia to search for signals of selection in this malaria endemic region. We found little geographic or temporal stratification of the genetic diversity a...

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Bibliographic Details
Main Authors: Amambua-Ngwa, Alfred, Park, Daniel J., Volkman, Sarah K., Barnes, Kayla G., Bei, Amy K., Lukens, Amanda K., Sene, Papa, Van Tyne, Daria, Ndiaye, Daouda, Wirth, Dyann F., Conway, David J., Neafsey, Daniel E., Schaffner, Stephen F.
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472499/