Lestaurtinib Inhibition of the JAK/STAT Signaling Pathway in Hodgkin Lymphoma Inhibits Proliferation and Induces Apoptosis

Lestaurtinib Inhibition of the JAK/STAT Signaling Pathway in Hodgkin Lymphoma Inhibits Proliferation and Induces Apoptosis

Standard cytotoxic chemotherapy for Hodgkin Lymphoma (HL) has changed little in 30 years; the treatment for patients with relapsed or refractory disease remains challenging and novel agents are under development. JAK/STAT constitutive activation plays an important role in the pathogenesis of HL. Les...

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Bibliographic Details
Main Authors: Diaz, Tania, Navarro, Alfons, Ferrer, Gerardo, Gel, Bernat, Gaya, Anna, Artells, Rosa, Bellosillo, Beatriz, Garcia-Garcia, Mar, Serrano, Sergi, Martínez, Antonio, Monzo, Mariano
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080386/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080386/

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