Icaritin Inhibits JAK/STAT3 Signaling and Growth of Renal Cell Carcinoma

Signal transducer and activator of transcription-3 (STAT3) is critical for cancer progression by regulating tumor cell survival, proliferation, and angiogenesis. Herein, we investigated the regulation of STAT3 activation and the therapeutic effects of Icaritin, a prenyl flavonoid derivative from Epi...

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Bibliographic Details
Main Authors: Li, Shasha, Priceman, Saul J., Xin, Hong, Zhang, Wang, Deng, Jiehui, Liu, Yong, Huang, Jiabin, Zhu, Wenshan, Chen, Mingjie, Hu, Wei, Deng, Xiaomin, Zhang, Jian, Yu, Hua, He, Guangyuan
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855768/