Single Cell Genome Amplification Accelerates Identification of the Apratoxin Biosynthetic Pathway from a Complex Microbial Assemblage
Filamentous marine cyanobacteria are extraordinarily rich sources of structurally novel, biomedically relevant natural products. To understand their biosynthetic origins as well as produce increased supplies and analog molecules, access to the clustered biosynthetic genes that encode for the assembl...
Main Authors: | Grindberg, Rashel V., Ishoey, Thomas, Brinza, Dumitru, Esquenazi, Eduardo, Coates, R. Cameron, Liu, Wei-ting, Gerwick, Lena, Dorrestein, Pieter C., Pevzner, Pavel, Lasken, Roger, Gerwick, William H. |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075265/ |
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