Sequence specific detection of DNA using nicking endonuclease signal amplification (NESA)

We have developed a new method for identifying specific single- or double-stranded DNA sequences called nicking endonuclease signal amplification (NESA). A probe and target DNA anneal to create a restriction site that is recognized by a strand-specific endonuclease that cleaves the probe into two pi...

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Bibliographic Details
Main Authors: Kiesling, Traci, Cox, Kendra, Davidson, Eugene A., Dretchen, Kenneth, Grater, Guy, Hibbard, Shannon, Lasken, Roger S., Leshin, Jonathan, Skowronski, Evan, Danielsen, Mark
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094061/