lncRNAs transactivate Staufen1-mediated mRNA decay by duplexing with 3'UTRs via Alu elements
Staufen1 (STAU1)-mediated mRNA decay (SMD) degrades translationally active mRNAs that bind the double-stranded (ds)RNA binding protein STAU1 within their 3'-untranslated regions (3'UTRs)1,2. Earlier studies defined the STAU1 binding site (SBS) within ADP ribosylation factor 1 (ARF1) mRNA a...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073508/ |