Potent Inhibition of Heterotopic Ossification by Nuclear Retinoic Acid Receptor γ Agonists

Potent Inhibition of Heterotopic Ossification by Nuclear Retinoic Acid Receptor γ Agonists

Heterotopic ossification (HO) consists of ectopic bone formation within soft tissues following surgery or trauma and can have debilitating consequences, but no definitive cure is available. Here we show that HO was essentially prevented in mice receiving nuclear retinoic acid receptor γ (RARγ) agoni...

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Bibliographic Details
Main Authors: Shimono, Kengo, Tung, Wei-en, Macolino, Christine, Chi, Amber Hsu-Tsai, Didizian, Johanna J., Mundy, Christina, Chandraratna, Roshantha A., Mishina, Yuji, Iwamoto, Motomi Enomoto, Pacifici, Maurizio, Iwamoto, Masahiro
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073031/

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