Enzymatic Blockade of the Ubiquitin-Proteasome Pathway

A viral ubiquitin-specific protease domain blocks cellular protein turnover by preemptive removal of ubiquitin chains and establishes an essential role for deubiquitylation in the removal of unfolded proteins from the endoplasmic reticulum.

Bibliographic Details
Main Authors:	Ernst, Robert, Claessen, Jasper H. L., Mueller, Britta, Sanyal, Sumana, Spooner, Eric, van der Veen, Annemarthe G., Kirak, Oktay, Schlieker, Christian D., Weihofen, Wilhelm A., Ploegh, Hidde L.
Format:	Online
Language:	English
Published:	Public Library of Science 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066133/

id	pubmed-3066133
recordtype	oai_dc
spelling	pubmed-30661332011-04-05 Enzymatic Blockade of the Ubiquitin-Proteasome Pathway Ernst, Robert Claessen, Jasper H. L. Mueller, Britta Sanyal, Sumana Spooner, Eric van der Veen, Annemarthe G. Kirak, Oktay Schlieker, Christian D. Weihofen, Wilhelm A. Ploegh, Hidde L. Research Article A viral ubiquitin-specific protease domain blocks cellular protein turnover by preemptive removal of ubiquitin chains and establishes an essential role for deubiquitylation in the removal of unfolded proteins from the endoplasmic reticulum. Public Library of Science 2011-03-29 /pmc/articles/PMC3066133/ /pubmed/21468303 http://dx.doi.org/10.1371/journal.pbio.1000605 Text en Ernst et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Ernst, Robert Claessen, Jasper H. L. Mueller, Britta Sanyal, Sumana Spooner, Eric van der Veen, Annemarthe G. Kirak, Oktay Schlieker, Christian D. Weihofen, Wilhelm A. Ploegh, Hidde L.
spellingShingle	Ernst, Robert Claessen, Jasper H. L. Mueller, Britta Sanyal, Sumana Spooner, Eric van der Veen, Annemarthe G. Kirak, Oktay Schlieker, Christian D. Weihofen, Wilhelm A. Ploegh, Hidde L. Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
author_facet	Ernst, Robert Claessen, Jasper H. L. Mueller, Britta Sanyal, Sumana Spooner, Eric van der Veen, Annemarthe G. Kirak, Oktay Schlieker, Christian D. Weihofen, Wilhelm A. Ploegh, Hidde L.
author_sort	Ernst, Robert
title	Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
title_short	Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
title_full	Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
title_fullStr	Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
title_full_unstemmed	Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
title_sort	enzymatic blockade of the ubiquitin-proteasome pathway
description	A viral ubiquitin-specific protease domain blocks cellular protein turnover by preemptive removal of ubiquitin chains and establishes an essential role for deubiquitylation in the removal of unfolded proteins from the endoplasmic reticulum.
publisher	Public Library of Science
publishDate	2011
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066133/
_version_	1611447412495220736

Enzymatic Blockade of the Ubiquitin-Proteasome Pathway

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