Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
A viral ubiquitin-specific protease domain blocks cellular protein turnover by preemptive removal of ubiquitin chains and establishes an essential role for deubiquitylation in the removal of unfolded proteins from the endoplasmic reticulum.
Main Authors: | , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2011
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066133/ |