SAINT: Probabilistic Scoring of Affinity Purification - Mass Spectrometry Data

SAINT: Probabilistic Scoring of Affinity Purification - Mass Spectrometry Data

We present SAINT (Significance Analysis of INTeractome), a computational tool that assigns confidence scores to protein-protein interaction data generated using affinity-purification coupled to mass spectrometry (AP-MS). The method utilizes label-free quantitative data and constructs separate distri...

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Bibliographic Details
Main Authors: Choi, Hyungwon, Larsen, Brett, Lin, Zhen-Yuan, Breitkreutz, Ashton, Mellacheruvu, Dattatreya, Fermin, Damian, Qin, Zhaohui S., Tyers, Mike, Gingras, Anne-Claude, Nesvizhskii, Alexey I.
Format: Online
Language:English
Published: 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064265/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064265/

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