Studies on rat liver nuclear DNA damaged by chemical carcinogen (3'-Me DAB) and AP DNA endonuclease. I. Purification and some properties of AP DNA endonucleases in rat liver chromatin.
Three kinds of apurinic/apyrimidinic (AP) DNA endonuclease, APcI, APcII, APcIII, were purified from rat liver chromatin through 1M KCl extraction, DEAE-trisacryl ion exchange chromatography. Sephadex G-150 gel filtration and AP DNA cellulose affinity chromatography. Activities of the purified APcI,...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Korean Academy of Medical Sciences
1990
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053769/ |