Studies on rat liver nuclear DNA damaged by chemical carcinogen (3'-Me DAB) and AP DNA endonuclease. II. Kinetic properties of AP DNA endonucleases in rat liver chromatin.
An experiment was designed to investigate the reaction mechanism of AP (apurinic or apyrimidinic) DNA endonucleases (APcI, APcII, APcIII) purified from rat liver chromatin. Sulfhydryl compounds (2-mercaptoethanol, dithiothreitol) brought about optimal activities of AP DNA endonucleases and N-ethylma...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Korean Academy of Medical Sciences
1990
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053764/ |