NEMO/IKKγ regulates an early NF-κB-independent cell death checkpoint during TNF signaling

NEMO/IKKγ regulates an early NF-κB-independent cell death checkpoint during TNF signaling

TNF receptor 1 (TNFR1) ligation can result in cell survival or cell death. What determines which of the two opposing responses is triggered is not fully understood. The current model suggests that it is the activation of the NF-κB pathway and its induction of pro-survival genes, or the lack thereof,...

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Bibliographic Details
Main Authors:	Legarda-Addison, Diana, Hase, Hidenori, O'Donnell, Marie Anne, Ting, Adrian T.
Format:	Online
Language:	English
Published:	2009
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728158/

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