TNF activation of NF-κB is essential for development of single-positive thymocytes

Seddon and colleagues study mice whose T cells lack both of the catalytic subunits of the IKK complex and show that impaired TNF receptor activation of NF-κB is responsible for their block in thymocyte development.

Bibliographic Details
Main Authors: Webb, Louise V., Ley, Steven C., Seddon, Benedict
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986527/