Activity-Dependent Modulation of Neural Circuit Synaptic Connectivity
In many nervous systems, the establishment of neural circuits is known to proceed via a two-stage process; (1) early, activity-independent wiring to produce a rough map characterized by excessive synaptic connections, and (2) subsequent, use-dependent pruning to eliminate inappropriate connections a...
Main Authors: | Tessier, Charles R., Broadie, Kendal |
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Format: | Online |
Language: | English |
Published: |
Frontiers Research Foundation
2009
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724028/ |
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