Genetic Controls Balancing Excitatory and Inhibitory Synaptogenesis in Neurodevelopmental Disorder Models

Proper brain function requires stringent balance of excitatory and inhibitory synapse formation during neural circuit assembly. Mutation of genes that normally sculpt and maintain this balance results in severe dysfunction, causing neurodevelopmental disorders including autism, epilepsy and Rett syn...

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Bibliographic Details
Main Authors: Gatto, Cheryl L., Broadie, Kendal
Format: Online
Language:English
Published: Frontiers Research Foundation 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059704/