Telomeres and disease

The telomeres of most eukaryotes are characterized by guanine-rich repeats synthesized by the reverse transcriptase telomerase. Complete loss of telomerase is tolerated for several generations in most species, but modestly reduced telomerase levels in human beings are implicated in bone marrow failu...

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Bibliographic Details
Main Author: Lansdorp, Peter M
Format: Online
Language:English
Published: Nature Publishing Group 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722246/