High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans
Telomerase is essential to maintain telomere length in most eukaryotes. Other functions for telomerase have been proposed but molecular mechanisms remain unclear. We studied Caenorhabditis elegans with a mutation in the trt-1 telomerase reverse transcriptase gene. Mutant animals showed a progressive...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326242/ |