CpG Methylation Controls Reactivation of HIV from Latency

DNA methylation of retroviral promoters and enhancers localized in the provirus 5′ long terminal repeat (LTR) is considered to be a mechanism of transcriptional suppression that allows retroviruses to evade host immune responses and antiretroviral drugs. However, the role of DNA methylation in the c...

Full description

Bibliographic Details
Main Authors: Blazkova, Jana, Trejbalova, Katerina, Gondois-Rey, Françoise, Halfon, Philippe, Philibert, Patrick, Guiguen, Allan, Verdin, Eric, Olive, Daniel, Van Lint, Carine, Hejnar, Jiri, Hirsch, Ivan
Format: Online
Language:English
Published: Public Library of Science 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722084/