Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin

Syncytin-1 and -2, human fusogenic glycoproteins encoded by the env genes of the endogenous retroviral loci ERVWE1 and ERVFRDE1, respectively, contribute to the differentiation of multinucleated syncytiotrophoblast in chorionic villi. In non-trophoblastic cells, however, the expression of syncytins...

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Bibliographic Details
Main Authors: Trejbalová, Kateřina, Blažková, Jana, Matoušková, Magda, Kučerová, Dana, Pecnová, Lubomíra, Vernerová, Zdenka, Heráček, Jiří, Hirsch, Ivan, Hejnar, Jiří
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203578/