Evidence for functional homology in the F-actin binding domains of gelsolin and alpha-actinin: implications for the requirements of severing and capping
The F-actin binding domains of gelsolin and alpha-actinin compete for the same site on actin filaments with similar binding affinities. Both contain tandem repeats of approximately 125 amino acids, the first of which is shown to contain the actin-binding site. We have replaced the F-actin binding do...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1992
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289707/ |