Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck.

Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck.

Tumours of the head and neck were examined for gene amplification and expression of the epidermal growth factor (EGF) receptor by Southern blot and Western blot analyses. The EGF receptor gene was found to be amplified in four (19%) of 21 squamous cell carcinomas. The EGF receptor was overexpressed...

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Bibliographic Details
Main Authors: Ishitoya, J., Toriyama, M., Oguchi, N., Kitamura, K., Ohshima, M., Asano, K., Yamamoto, T.
Format: Online
Language:English
Published: Nature Publishing Group 1989
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247138/

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