Metoclopramide enhances the effect of cisplatin on xenografted squamous cell carcinoma of the head and neck.
The chromatin-bound enzyme adenosine diphosphate ribosyl transferase is activated by DNA-damaging agents. Substances that inhibit the enzyme, such as benzamide analogues, are known to increase the cytotoxicity of ionising radiation and cytotoxic drugs. The purpose of the present study was to investi...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Nature Publishing Group
1989
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247013/ |