Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development
Dlx homeobox genes are first expressed in embryonic retina at E11.5. The Dlx1/Dlx2 null retina has a reduced ganglion cell layer (GCL), with loss of late-born differentiated retinal ganglion cells (RGCs) due to increased apoptosis. TrkB signaling is proposed to regulate the dynamics of RGC apoptosis...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Oxford University Press
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241891/ |