Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development

Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development

Dlx homeobox genes are first expressed in embryonic retina at E11.5. The Dlx1/Dlx2 null retina has a reduced ganglion cell layer (GCL), with loss of late-born differentiated retinal ganglion cells (RGCs) due to increased apoptosis. TrkB signaling is proposed to regulate the dynamics of RGC apoptosis...

Full description

Bibliographic Details
Main Authors: de Melo, Jimmy, Zhou, Qing-Ping, Zhang, Qi, Zhang, Shunzhen, Fonseca, Mario, Wigle, Jeffrey T., Eisenstat, David D.
Format: Online
Language:English
Published: Oxford University Press 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241891/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241891/

Similar Items