miRBase: tools for microRNA genomics

miRBase is the central online repository for microRNA (miRNA) nomenclature, sequence data, annotation and target prediction. The current release (10.0) contains 5071 miRNA loci from 58 species, expressing 5922 distinct mature miRNA sequences: a growth of over 2000 sequences in the past 2 years. miRB...

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Main Authors: Griffiths-Jones, Sam, Saini, Harpreet Kaur, van Dongen, Stijn, Enright, Anton J.
Format: Online
Language:English
Published: Oxford University Press 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238936/
id pubmed-2238936
recordtype oai_dc
spelling pubmed-22389362008-02-12 miRBase: tools for microRNA genomics Griffiths-Jones, Sam Saini, Harpreet Kaur van Dongen, Stijn Enright, Anton J. Articles miRBase is the central online repository for microRNA (miRNA) nomenclature, sequence data, annotation and target prediction. The current release (10.0) contains 5071 miRNA loci from 58 species, expressing 5922 distinct mature miRNA sequences: a growth of over 2000 sequences in the past 2 years. miRBase provides a range of data to facilitate studies of miRNA genomics: all miRNAs are mapped to their genomic coordinates. Clusters of miRNA sequences in the genome are highlighted, and can be defined and retrieved with any inter-miRNA distance. The overlap of miRNA sequences with annotated transcripts, both protein- and non-coding, are described. Finally, graphical views of the locations of a wide range of genomic features in model organisms allow for the first time the prediction of the likely boundaries of many miRNA primary transcripts. miRBase is available at http://microrna.sanger.ac.uk/. Oxford University Press 2008-01 2007-11-08 /pmc/articles/PMC2238936/ /pubmed/17991681 http://dx.doi.org/10.1093/nar/gkm952 Text en © 2007 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Griffiths-Jones, Sam
Saini, Harpreet Kaur
van Dongen, Stijn
Enright, Anton J.
spellingShingle Griffiths-Jones, Sam
Saini, Harpreet Kaur
van Dongen, Stijn
Enright, Anton J.
miRBase: tools for microRNA genomics
author_facet Griffiths-Jones, Sam
Saini, Harpreet Kaur
van Dongen, Stijn
Enright, Anton J.
author_sort Griffiths-Jones, Sam
title miRBase: tools for microRNA genomics
title_short miRBase: tools for microRNA genomics
title_full miRBase: tools for microRNA genomics
title_fullStr miRBase: tools for microRNA genomics
title_full_unstemmed miRBase: tools for microRNA genomics
title_sort mirbase: tools for microrna genomics
description miRBase is the central online repository for microRNA (miRNA) nomenclature, sequence data, annotation and target prediction. The current release (10.0) contains 5071 miRNA loci from 58 species, expressing 5922 distinct mature miRNA sequences: a growth of over 2000 sequences in the past 2 years. miRBase provides a range of data to facilitate studies of miRNA genomics: all miRNAs are mapped to their genomic coordinates. Clusters of miRNA sequences in the genome are highlighted, and can be defined and retrieved with any inter-miRNA distance. The overlap of miRNA sequences with annotated transcripts, both protein- and non-coding, are described. Finally, graphical views of the locations of a wide range of genomic features in model organisms allow for the first time the prediction of the likely boundaries of many miRNA primary transcripts. miRBase is available at http://microrna.sanger.ac.uk/.
publisher Oxford University Press
publishDate 2008
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238936/
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