Regulation by Na+ and Ca2+ of renal epithelial Na+ channels reconstituted into planar lipid bilayers
Purified bovine renal epithelial Na+ channels when reconstituted into planar lipid bilayers displayed a specific orientation when the membrane was clamped to -40 mV (cis-side) during incorporation. The trans-facing portion of the channel was extracellular (i.e., amiloride- sensitive), whereas the ci...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1995
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229271/ |