A phase II study of regional 2-weekly 5-fluorouracil infusion with intravenous folinic acid in the treatment of colorectal liver metastases.

Forty patients with unresectable colorectal metastases confined to the liver were evaluated in a phase II study. 5-Fluorouracil (5-FU) was delivered via a surgically placed hepatic artery catheter. Patients received folinic acid (200 mg m-2) intravenously over 2 h followed by a loading dose of intra...

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Bibliographic Details
Main Authors: Howell, J. D., McArdle, C. S., Kerr, D. J., Buckles, J., Ledermann, J. A., Taylor, I., Gallagher, H. J., Budden, J.
Format: Online
Language:English
Published: Nature Publishing Group 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228150/