Synthesis and Biological Analysis of Thiotetra(ethylene glycol) monomethyl Ether-Functionalized Porphyrazines: Cellular Uptake and Toxicity Studies
The porphyrazines (pzs), a class of porphyrin analogues, are being investigated for their potential use as tumor imaging/therapeutic agents. We here examine six peripherally-functionalized M[pz(AnB4-n)] pzs with n=4, 3, or 2 (in a trans conformation) and M = H2 or Zn, where A is an [S((CH2)2O)4Me]2...
Main Authors: | Lee, Sangwan, Vesper, Benjamin J., Zong, Hong, Hammer, Neal D., Elseth, Kim M., Barrett, Anthony G. M., Hoffman, Brian M., Radosevich, James A. |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2008
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225588/ |
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