Modulation of Aire regulates the expression of tissue-restricted antigens
Intrathymic expression of tissue-restricted antigens (TRAs) has been viewed as the key element in the induction of central tolerance and recently, a central role for the autoimmune regulator (Aire) has been suggested in this process. The aim of this study was to establish whether down or up-regulati...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Pergamon Press
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994210/ |