Active Nuclear Import and Export Is Independent of Lumenal Ca2+ Stores in Intact Mammalian Cells
The nuclear pore complex (NPC) mediates communication between the cytoplasm and nucleus in eukaryotic cells. Active transport of large polypeptides as well as passive diffusion of smaller (≈10 kD) macromolecules through the NPC can be inhibited by depletion of intracellular Ca2+ stores. However, the...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
1999
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223372/ |