Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells

Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells

Oxidative folding facilitates protein import into the mitochondrial intermembrane space. An analysis of the process in intact mammalian cells reveals the contributions of Mia40, ALR, glutathione, and the membrane potential. Proteins that rely on oxidative folding remain stable and reduced in the cyt...

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Bibliographic Details
Main Authors: Fischer, Manuel, Horn, Sebastian, Belkacemi, Anouar, Kojer, Kerstin, Petrungaro, Carmelina, Habich, Markus, Ali, Muna, Küttner, Victoria, Bien, Melanie, Kauff, Frank, Dengjel, Jörn, Herrmann, Johannes M., Riemer, Jan
Format: Online
Language:English
Published: The American Society for Cell Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708723/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708723/

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