Role of Antigen-Presenting Cells in Mediating Tolerance and Autoimmunity

The mechanisms that determine whether receptor stimulation leads to lymphocyte tolerance versus activation remain poorly understood. We have used rat insulin promoter (RIP)-gp/P14 double-transgenic mice expressing the lymphocytic choriomeningitis virus (LCMV) glycoprotein (gp) on pancreatic β-islet...

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Bibliographic Details
Main Authors: Garza, Kristine M., Chan, Steven M., Suri, Rakesh, Nguyen, Linh T., Odermatt, Bernhard, Schoenberger, Stephen P., Ohashi, Pamela S.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213533/