Induction of tolerance to autoimmune diabetes with islet antigens
The development of T cell tolerance to self-antigens is imparted principally through negative selection events during thymic ontogeny. However, this tolerance may be limited to antigens that are expressed in the thymus, and additional mechanisms are probably required to regulate autoimmune responses...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1992
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119389/ |