Cross-Presentation of Glycoprotein 96–Associated Antigens on Major Histocompatibility Complex Class I Molecules Requires Receptor-Mediated Endocytosis

Cross-Presentation of Glycoprotein 96–Associated Antigens on Major Histocompatibility Complex Class I Molecules Requires Receptor-Mediated Endocytosis

Heat shock proteins (HSPs) like glycoprotein (gp)96 (glucose-regulated protein 94 [grp94]) are able to induce specific cytotoxic T lymphocyte (CTL) responses against cells from which they originate. Here, we demonstrate that for CTL activation by gp96-chaperoned peptides, specific receptor-mediated...

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Bibliographic Details
Main Authors: Singh-Jasuja, Harpreet, Toes, René E.M., Spee, Pieter, Münz, Christian, Hilf, Norbert, Schoenberger, Stephen P., Ricciardi-Castagnoli, Paola, Neefjes, Jacques, Rammensee, Hans-Georg, Arnold-Schild, Danièle, Schild, Hansjörg
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213530/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213530/

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