Enhanced Growth of Primary Tumors in Cancer-Prone Mice after Immunization against the Mutant Region of an Inherited Oncoprotein

Enhanced Growth of Primary Tumors in Cancer-Prone Mice after Immunization against the Mutant Region of an Inherited Oncoprotein

One major objective of tumor immunologists is to prevent cancer development in individuals at high risk. (TG.AC × C57BL/6)F1 mice serve as a model for testing the feasibility of this objective. The mice carry in the germline a mutant ras oncogene that has an arginine at codon 12 instead of glycine p...

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Bibliographic Details
Main Authors: Siegel, Christopher T., Schreiber, Karin, Meredith, Stephen C., Beck-Engeser, Gabriele B., Lancki, David W., Lazarski, Christopher A., Fu, Yang-Xin, Rowley, Donald A., Schreiber, Hans
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213520/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213520/

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