Point Mutation in Essential Genes with Loss or Mutation of the Second Allele: Relevance to the Retention of Tumor-Specific Antigens

Point Mutation in Essential Genes with Loss or Mutation of the Second Allele: Relevance to the Retention of Tumor-Specific Antigens

Antigens that are tumor specific yet retained by tumor cells despite tumor progression offer stable and specific targets for immunologic and possibly other therapeutic interventions. Therefore, we have studied two CD4+ T cell–recognized tumor-specific antigens that were retained during evolution of...

Full description

Bibliographic Details
Main Authors: Beck-Engeser, Gabriele B., Monach, Paul A., Mumberg, Dominik, Yang, Farley, Wanderling, Sherry, Schreiber, Karin, Espinosa, Rafael, Le Beau, Michelle M., Meredith, Stephen C., Schreiber, Hans
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193475/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193475/

Similar Items