CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

Tumor growth promotes the expansion of CD4+CD25+ regulatory T (T reg) cells that counteract T cell–mediated immune responses. An inverse correlation between natural killer (NK) cell activation and T reg cell expansion in tumor-bearing patients, shown here, prompted us to address the role of T reg ce...

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Bibliographic Details
Main Authors: Ghiringhelli, François, Ménard, Cédric, Terme, Magali, Flament, Caroline, Taieb, Julien, Chaput, Nathalie, Puig, Pierre E., Novault, Sophie, Escudier, Bernard, Vivier, Eric, Lecesne, Axel, Robert, Caroline, Blay, Jean-Yves, Bernard, Jacky, Caillat-Zucman, Sophie, Freitas, Antonio, Tursz, Thomas, Wagner-Ballon, Orianne, Capron, Claude, Vainchencker, William, Martin, François, Zitvogel, Laurence
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213209/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213209/

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