A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells

A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells

Dendritic cells (DC) produce interleukin-12 (IL-12) in response to Toll-like receptor (TLR) activation. Two major TLR signaling pathways participate in the response to pathogens: the nuclear factor-κB (NF-κB)–dependent pathway leading to inflammatory cytokine secretion including IL-12 and the interf...

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Bibliographic Details
Main Authors: Gautier, Grégory, Humbert, Martine, Deauvieau, Florence, Scuiller, Mathieu, Hiscott, John, Bates, Elizabeth E.M., Trinchieri, Giorgio, Caux, Christophe, Garrone, Pierre
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213193/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213193/

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