The Autocrine/Paracrine Loop After Myocardial Stretch: Mineralocorticoid Receptor Activation

The stretch of cardiac muscle increases developed force in two phases. The first phase, which occurs rapidly, constitutes the well-known Frank-Starling mechanism and it is generally attributed to enhanced myofilament responsiveness to Ca2+. The second phase or slow force response (SFR) occurs gradua...

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Bibliographic Details
Main Authors: Ennis, Irene L, Aiello, Ernesto A, Cingolani, Horacio E, Pérez, Néstor G
Format: Online
Language:English
Published: Bentham Science Publishers 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780348/