The Autocrine/Paracrine Loop After Myocardial Stretch: Mineralocorticoid Receptor Activation
The stretch of cardiac muscle increases developed force in two phases. The first phase, which occurs rapidly, constitutes the well-known Frank-Starling mechanism and it is generally attributed to enhanced myofilament responsiveness to Ca2+. The second phase or slow force response (SFR) occurs gradua...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Bentham Science Publishers
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780348/ |