A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice
A combination of genetic and environmental factors can cause autoimmune disease in animals. SKG mice, which are genetically prone to develop autoimmune arthritis, fail to develop the disease under a microbially clean condition, despite active thymic production of arthritogenic autoimmune T cells and...
Main Authors: | , , , , , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2005
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213107/ |