A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

A combination of genetic and environmental factors can cause autoimmune disease in animals. SKG mice, which are genetically prone to develop autoimmune arthritis, fail to develop the disease under a microbially clean condition, despite active thymic production of arthritogenic autoimmune T cells and...

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Bibliographic Details
Main Authors: Yoshitomi, Hiroyuki, Sakaguchi, Noriko, Kobayashi, Katsuya, Brown, Gordon D., Tagami, Tomoyuki, Sakihama, Toshiko, Hirota, Keiji, Tanaka, Satoshi, Nomura, Takashi, Miki, Ichiro, Gordon, Siamon, Akira, Shizuo, Nakamura, Takashi, Sakaguchi, Shimon
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213107/