The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection

The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection

Viral infection and stimulation with lipopolysaccharide (LPS) or double stranded RNA (dsRNA) induce phosphorylation of interferon (IFN) regulatory factor (IRF)-3 and its translocation to the nucleus, thereby leading to the IFN-β gene induction. Recently, two IκB kinase (IKK)–related kinases, inducib...

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Bibliographic Details
Main Authors: Hemmi, Hiroaki, Takeuchi, Osamu, Sato, Shintaro, Yamamoto, Masahiro, Kaisho, Tsuneyasu, Sanjo, Hideki, Kawai, Taro, Hoshino, Katsuaki, Takeda, Kiyoshi, Akira, Shizuo
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212809/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212809/

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